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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX1B All Species: 48.48
Human Site: S207 Identified Species: 82.05
UniProt: P61266 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61266 NP_443106.1 288 33245 S207 E I I K L E T S I R E L H D M
Chimpanzee Pan troglodytes XP_001146812 288 32492 S208 E I I K L E N S I R E L H D M
Rhesus Macaque Macaca mulatta XP_001103901 336 38070 S255 E I I K L E T S I R E L H D M
Dog Lupus familis XP_547038 348 39606 S215 E I I K L E T S I R E L H D M
Cat Felis silvestris
Mouse Mus musculus O35526 288 33036 S208 E I I K L E T S I R E L H D M
Rat Rattus norvegicus P32851 288 33049 S208 E I I K L E N S I R E L H D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_990405 282 32496 S200 E I I Y L E T S I R E L H D M
Frog Xenopus laevis NP_001086322 286 32704 S206 D I V R L E S S L K E L H D M
Zebra Danio Brachydanio rerio NP_571598 288 33347 S207 E I I K L E N S I R E L H D M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24547 291 33630 S211 D I M K L E T S I K E L H D M
Honey Bee Apis mellifera XP_393760 291 33455 S212 D I I K L E N S I R E L H D M
Nematode Worm Caenorhab. elegans O16000 291 33234 S209 D I M K L E S S I R E L H D M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZQZ8 305 34465 V216 I Q E R H D T V K E I E R S L
Baker's Yeast Sacchar. cerevisiae P39926 295 33715 L207 R H Q E L L K L E K T M A E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.7 85.1 75.5 N.A. 84 83.6 N.A. N.A. 84.7 62.5 96.8 N.A. 68.7 66.3 59.1 N.A.
Protein Similarity: 100 88.1 85.7 78.1 N.A. 94.4 94 N.A. N.A. 87.5 84 98.2 N.A. 82.1 79 78.3 N.A.
P-Site Identity: 100 93.3 100 100 N.A. 100 93.3 N.A. N.A. 93.3 60 93.3 N.A. 80 86.6 80 N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 100 93.3 N.A. N.A. 93.3 100 93.3 N.A. 100 93.3 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.9 26.7 N.A.
Protein Similarity: N.A. N.A. N.A. 47.8 49.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 29 0 0 0 0 8 0 0 0 0 0 0 0 86 0 % D
% Glu: 58 0 8 8 0 86 0 0 8 8 86 8 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 8 0 0 0 0 0 0 0 86 0 0 % H
% Ile: 8 86 65 0 0 0 0 0 79 0 8 0 0 0 0 % I
% Lys: 0 0 0 72 0 0 8 0 8 22 0 0 0 0 0 % K
% Leu: 0 0 0 0 93 8 0 8 8 0 0 86 0 0 15 % L
% Met: 0 0 15 0 0 0 0 0 0 0 0 8 0 0 86 % M
% Asn: 0 0 0 0 0 0 29 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 15 0 0 0 0 0 72 0 0 8 0 0 % R
% Ser: 0 0 0 0 0 0 15 86 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 50 0 0 0 8 0 0 0 0 % T
% Val: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _